Donadio M F, Kozlowski P B, Kaplan H, Wisniewski H M, Majkowski J
Brain Res. 1982 Feb 25;234(2):263-73. doi: 10.1016/0006-8993(82)90867-8.
The relationship between seizure propensity and the vascular anatomy of the anterior cerebral arteries, or stroke induced by unilateral ligation of the common carotid artery, was investigated utilizing well differentiated colonies of seizure-prone (SP) and non-seizure-prone (NSP) gerbils. Twenty SP and 20 NSP gerbils were perfused with a latex dye and the vascular patterns of the anterior cerebral arteries (ACA) were analyzed. In addition, 30 SP and 30 NSP gerbils were subjected to unilateral ligation of the common carotid artery and the number developing stroke (determined by clinical observation as well as by microscopic examination of the brain) was recorded. We found that in all animals the ACAs formed a fused-central vessel which vascularized the olfactory bulbs, as well as two lateral vessels (rostral arteries) that vascularized a previously undescribed nasal plexus. Neither the vascular pattern of the ACA, nor the frequency of occurrence of stroke following unilateral ligation was related to seizure propensity.
利用癫痫易感（SP）和非癫痫易感（NSP）沙鼠的高度分化菌落，研究了癫痫易感性与大脑前动脉血管解剖结构或单侧颈总动脉结扎诱发的中风之间的关系。给20只SP沙鼠和20只NSP沙鼠灌注乳胶染料，并分析大脑前动脉（ACA）的血管模式。此外，对30只SP沙鼠和30只NSP沙鼠进行单侧颈总动脉结扎，并记录发生中风的数量（通过临床观察以及大脑显微镜检查确定）。我们发现，在所有动物中，ACA形成了一条融合的中央血管，为嗅球提供血液供应，还有两条侧支血管（ Rostral动脉），为一个以前未描述的鼻丛提供血液供应。ACA的血管模式和单侧结扎后中风的发生频率均与癫痫易感性无关。
