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一种用导管内镭治疗癌性胆管梗阻的新方法。

A new method for treating carcinomatous biliary obstruction with intracatheter radium.

作者信息

Conroy R M, Shahbazian A A, Edwards K C, Moran E M, Swingle K F, Lewis G J, Pribram H F

出版信息

Cancer. 1982 Apr 1;49(7):1321-7. doi: 10.1002/1097-0142(19820401)49:7<1321::aid-cncr2820490702>3.0.co;2-s.

Abstract

We describe a new method for relieving biliary obstruction due to malignant solid tumors. The method consists of placement of radium needles in a Ring biliary drainage catheter for three days. After removing the radium needles, the catheter is left in place to allow for repair of irradiated tissues, then it is removed. The object is to leave the patient with a patent biliary tree without a biliary drainage prosthesis. The clinical course of six patients treated by this method is described, and the autopsy findings in three cases are outlined. Three patients died with a serum total bilirubin ranging from 1--4.5 mg/100 ml, two to three months after removing the drainage catheter. Two patients died before the bile drainage catheter could be removed. One patient is alive with a bile drainage catheter in place. Possible modifications in technique and catheters are being considered.

摘要

我们描述了一种用于缓解恶性实体瘤所致胆道梗阻的新方法。该方法包括将镭针置于环形胆道引流导管中三天。取出镭针后,将导管留置原位以利于受照射组织的修复,然后再将其取出。目的是使患者的胆道保持通畅,而无需胆道引流假体。本文描述了采用该方法治疗的6例患者的临床病程,并概述了3例患者的尸检结果。3例患者在拔除引流导管后两至三个月死亡,血清总胆红素范围为1 - 4.5mg/100ml。2例患者在胆汁引流导管能够拔除之前死亡。1例患者带胆汁引流导管存活。正在考虑对技术和导管进行可能的改进。

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