Marshall M E, Trump D L
Cancer. 1982 Apr 1;49(7):1496-9. doi: 10.1002/1097-0142(19820401)49:7<1496::aid-cncr2820490731>3.0.co;2-3.
Clinically detectable pulmonic stenosis resulting from compression of the pulmonary artery or right ventricular outflow tract by mediastinal tumors is uncommon. This report describes the occurrence of pulmonic stenosis secondary to a mediastinal tumor in a patient with Hodgkin's disease and in two patients with non-Hodgkin's lymphomas. Review of 35 published reports reveals that teratomas (ten cases) and Hodgkin's disease (eight cases) are the neoplasms most frequently reported to cause extrinsic pulmonic stenosis. Chest pain and dyspnea were the symptoms most commonly reported and a pulmonic ejection murmur was the most common physical finding in patients with acquired pulmonic stenosis. The prognostic significance of acquired pulmonic stenosis. The prognostic significance of acquired pulmonic stenosis secondary to mediastinal tumors is unclear.
临床上可检测到的由纵隔肿瘤压迫肺动脉或右心室流出道引起的肺动脉狭窄并不常见。本报告描述了1例霍奇金病患者和2例非霍奇金淋巴瘤患者继发于纵隔肿瘤的肺动脉狭窄情况。回顾35篇已发表的报告发现，畸胎瘤（10例）和霍奇金病（8例）是最常报告的可导致外在性肺动脉狭窄的肿瘤。胸痛和呼吸困难是最常报告的症状，肺动脉喷射性杂音是获得性肺动脉狭窄患者最常见的体格检查发现。获得性肺动脉狭窄的预后意义。继发于纵隔肿瘤的获得性肺动脉狭窄的预后意义尚不清楚。
