Abreu I, David-Ferreira J F
Cell Tissue Res. 1982;222(1):143-52. doi: 10.1007/BF00218294.
The ultrastructure of the seminiferous tubules was studied in rats that had been subjected to whole body irradiation on the 19th day of gestation. The seminiferous tubules from 3 months-old irradiated animals are devoid of germ cells and contain only Sertoli cells. Compared with controls of the same age, the seminiferous tubule basal membrane is thickened and multilayered and several alterations are observed in the Sertoli cells. The most characteristic of these alterations are: (a) an abnormal number of nuclear heterochromatin clumps, (b) the presence of numerous cytoplasmic vacuoles and various sized lipid droplets, (c) elaborate interdigitations and junctions between adjacent cells, and (d) the presence of anomalous ectoplasmic specializations disposed perpendicularly to the Sertoli cell membrane.
对在妊娠第19天接受全身照射的大鼠的生精小管超微结构进行了研究。3个月大的受辐照动物的生精小管没有生殖细胞，仅含有支持细胞。与相同年龄的对照组相比，生精小管基底膜增厚且多层化，并且在支持细胞中观察到几种改变。这些改变最典型的是：(a)核异染色质团块数量异常；(b)存在大量细胞质空泡和各种大小的脂滴；(c)相邻细胞之间有精细的相互交错和连接；(d)存在垂直于支持细胞膜排列的异常外质特化结构。
