Felman Y M, Nikitas J A
Cutis. 1982 Feb;29(2):122-4, 128, 133, 136.
Syphilis is an infectious spirochetal disease caused by Treponema pallidum. The disease is transmitted from person to person during sexual intercourse, congenitally by an infected pregnant woman to the fetus in utero, or very rarely, non-sexually. In its natural course, syphilis is characterized by an acute infectious primary and secondary stage, followed by a subclinical course of latency which may persist for years, or may progress in a minority of patients to a noninfectious late symptomatic stage where active involvement of the central nervous system, the cardiovascular system or localized gummatous destructive lesions may occur. This article reviews the clinical features and management of primary syphilis.
梅毒是由梅毒螺旋体引起的一种传染性螺旋体病。该病通过性交在人与人之间传播，由感染的孕妇在子宫内传给胎儿，或极罕见地通过非性途径传播。在其自然病程中，梅毒的特征是有急性感染性的一期和二期阶段，随后是可能持续数年的亚临床潜伏期，少数患者可能进展到非感染性的晚期症状阶段，此时可能会出现中枢神经系统、心血管系统的活动性受累或局部树胶肿性破坏性病变。本文综述一期梅毒的临床特征及治疗。
