Lietz H, Meissner K
Dtsch Med Wochenschr. 1982 Feb 26;107(8):299-303. doi: 10.1055/s-2008-1069921.
Within a period of four years twelve cases of short small bowel stenoses were seen requiring surgical removal by resection because of acute ileus. Two of these cases were considered examples of an eosinophilic enteritis. The remaining cases were mostly men of an average age of 63 years. With one exception, they had been treated for cardiovascular diseases with various drugs, mostly potassium, digitalis and reserpine preparations. The intestinal stenoses were 1-3.5 cm in length with a constriction down to 1 mm diameter. Obviously, these obstructions develop from an infarct-like necrosis of the mucosa via a circular ulcer; the narrowing of the intestinal lumen is chiefly due to fibromuscular hyperplasia of the submucous coat. The morphological changes agree with the findings known from ischaemic intestinal lesions as well as with those in jejunal ulcus simplex. Hence, it appears justified to interpret them as ischaemic intestinal stricture. However, an additional and as yet unknown damaging factor seems to be involved.
在四年时间里，共发现12例短小肠狭窄病例，因急性肠梗阻需要通过切除手术移除。其中2例被认为是嗜酸性肠炎的例子。其余病例大多为男性，平均年龄63岁。除1例外，他们都曾使用各种药物治疗心血管疾病，主要是钾、洋地黄和利血平制剂。肠道狭窄长度为1 - 3.5厘米，缩窄至直径1毫米。显然，这些梗阻是由黏膜的梗死样坏死经环形溃疡发展而来；肠腔狭窄主要是由于黏膜下层的纤维肌肉增生。形态学变化与缺血性肠道病变以及空肠单纯性溃疡的表现相符。因此，将它们解释为缺血性肠道狭窄似乎是合理的。然而，似乎还涉及一个额外的、尚不明确的损伤因素。
