Nilsson L, Wikland M, Hamberger L
Fertil Steril. 1982 Jan;37(1):30-4. doi: 10.1016/s0015-0282(16)45972-8.
The study was undertaken to explore the time required for the selection and ovulation of a dominant follicle after interference with the normal menstrual cycle of fertile women. At routine laparotomy (sterilization) a leading follicle or a fresh corpus luteum was excised, and the day of the next ovulation was estimated by monitoring of serum levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), progesterone, and 17 beta-estradiol and by registration of the growth of the follicles through ultrasonic scanning. The results are in accordance with earlier observations in the rhesus monkey demonstrating that the recruitment and selection of an ovulation-competent follicle takes 12 to 14 days in the primate. Since this time is close to the length of the normal follicular phase and approximately the same after follicle-ectomy and luteectomy, the results suggest an importance of local factors in regulating follicle recruitment.
本研究旨在探讨干扰育龄妇女正常月经周期后，优势卵泡选择和排卵所需的时间。在常规剖腹手术（绝育）时，切除一个主导卵泡或一个新鲜的黄体，并通过监测血清促黄体生成素（LH）、促卵泡生成素（FSH）、孕酮和17β-雌二醇水平以及通过超声扫描记录卵泡生长情况来估计下次排卵的日期。结果与恒河猴早期的观察结果一致，表明在灵长类动物中，有排卵能力的卵泡的募集和选择需要12至14天。由于这段时间接近正常卵泡期的长度，并且在卵泡切除和黄体切除后大致相同，因此结果表明局部因素在调节卵泡募集方面具有重要作用。
