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轻度子宫内膜异位症不孕患者的保守手术与期待治疗对比

Conservative surgery versus expectant management for the infertile patient with mild endometriosis.

作者信息

Schenken R S, Malinak L R

出版信息

Fertil Steril. 1982 Feb;37(2):183-6. doi: 10.1016/s0015-0282(16)46036-x.

DOI:10.1016/s0015-0282(16)46036-x
PMID:7060768
Abstract

During an 8-year period, the records of 90 patients with mild pelvic endometriosis diagnosed by endoscopy were reviewed to determine whether conservative surgical treatment resulted in higher pregnancy rates than expectant management. Forty-five patients were found to have mild endometriosis as the only abnormality in a complete fertility workup. Sixteen patients were managed expectantly, and 75% became pregnant in 1 year. Twenty-nine patients had conservative surgery, and 72.4% conceived in 1 year. This surgery-to-pregnancy interval was similar in both groups. Sixty patients had mild endometriosis only or mild endometriosis and anovulation corrected by clomiphene citrate. The pregnancy rate in 1 year was 72.2% in 18 patients managed expectantly and 76.2% in 42 patients treated with conservative surgery. The surgery-to-pregnancy interval was 5 and 6 months, respectively. These results suggest that expectant management should be considered prior to medical or surgical treatment of infertile patients with mild endometriosis.

摘要

在8年期间,对90例经内镜诊断为轻度盆腔子宫内膜异位症患者的记录进行回顾,以确定保守性手术治疗是否比期待治疗有更高的妊娠率。45例患者在完整的生育力检查中被发现仅有轻度子宫内膜异位症这一异常情况。16例患者接受期待治疗,75%在1年内怀孕。29例患者接受了保守性手术,72.4%在1年内受孕。两组患者从手术到怀孕的间隔相似。60例患者仅有轻度子宫内膜异位症或患有轻度子宫内膜异位症且通过枸橼酸氯米芬纠正了无排卵情况。18例接受期待治疗的患者1年内的妊娠率为72.2%,42例接受保守性手术治疗的患者妊娠率为76.2%。从手术到怀孕的间隔分别为5个月和6个月。这些结果表明,对于患有轻度子宫内膜异位症的不孕患者,在进行药物或手术治疗之前应考虑期待治疗。

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引用本文的文献

1
The treatment of mild endometriosis with laser laparoscopy: a two-step treatment analysis of patients whose primary therapy was successful.激光腹腔镜治疗轻度子宫内膜异位症:对初始治疗成功患者的两步治疗分析
JSLS. 2006 Jan-Mar;10(1):30-6.
2
The success of laser laparoscopy in the treatment of endometriosis: a two-step analysis.激光腹腔镜检查术治疗子宫内膜异位症的疗效:两步分析
JSLS. 2001 Jan-Mar;5(1):21-7.
3
Drugs in the treatment of female infertility. Recent advances.治疗女性不孕症的药物。最新进展。
Drugs. 1986 Aug;32(2):169-77. doi: 10.2165/00003495-198632020-00004.
4
Successful treatment of asymptomatic endometriosis: does it benefit infertile women?无症状子宫内膜异位症的成功治疗:对不孕女性有益吗?
Br Med J (Clin Res Ed). 1987 May 2;294(6580):1117-9. doi: 10.1136/bmj.294.6580.1117.
5
Endometriosis.子宫内膜异位症
BMJ. 1990 Jul 28;301(6745):189-90. doi: 10.1136/bmj.301.6745.189.