高剂量雌激素处理后正常血压大鼠的血压和去甲肾上腺素浓度的年龄差异
Age differences in blood pressure and norepinephrine concentration in normotensive rats after higher doses of estrogen.
作者信息
Lew G M
出版信息
Gen Pharmacol. 1982;13(1):75-8. doi: 10.1016/0306-3623(82)90017-9.
PMID:7060926
Abstract
- Normotensive rats (3 months old) showed 6-9% increases in blood pressure (B.P.) after high doses of estrogen, with increases in hypothalamic and adrenal norepinephrine (NE). 2. Older normotensive rats (6 months old) showed 4-11% increases in B.P. after high doses of estrogen with a decrease in brainstem NE.
摘要
- 正常血压的大鼠（3个月大）在高剂量雌激素作用后血压升高6 - 9%，同时下丘脑和肾上腺去甲肾上腺素（NE）增加。2. 年龄较大的正常血压大鼠（6个月大）在高剂量雌激素作用后血压升高4 - 11%，而脑干NE减少。
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