Arons M S, Fernando L, Polayes I M
J Hand Surg Am. 1982 Jan;7(1):47-52. doi: 10.1016/s0363-5023(82)80013-0.
Pasteurella multocida is a common cause of infection following bites or scratches caused by dogs and (especially) cats. It is rarely reported, however, and apparently often overlooked as a pathogen. The typical clinical manifestation is a rapidly developing cellulitis at the site of injury. The infection is potentially dangerous and can cause a chronic local infection of deep tissues and osteomyelitis. It responds well to several antimicrobials, with penicillin being drug of choice. Fifty-five patients are reported--72% with cat bites and/or scratches and 28% with dog bites. Ninety-two percent of the wounds went deeply through the skin. All patients presented for treatment 12 to 72 hours after receiving the animal wounds to their hands. Drainage from all wounds was serosanguineous or purulent, and cultures taken were positive for P. multocida. All of the wounds responded to surgical drainage and penicillin. One patient developed osteomyelitis. The acute onset of cellulitis, lymphangitis, and serosanguineous or purulent drainage from hand wounds 12 to 24 hours after cat or dog bites should suggest P. multocida as the predominant etiologic agent. Immediate surgical drainage and penicillin therapy is the treatment of choice.
多杀巴斯德菌是狗（尤其是猫）咬伤或抓伤后感染的常见原因。然而，其报道很少，显然常被忽视是一种病原体。典型的临床表现是受伤部位迅速发展的蜂窝织炎。该感染有潜在危险，可导致深部组织的慢性局部感染和骨髓炎。它对多种抗菌药物反应良好，青霉素是首选药物。本文报道了55例患者，其中72%为猫咬伤和/或抓伤，28%为狗咬伤。92%的伤口深达皮肤。所有患者在手部被动物致伤后12至72小时就诊。所有伤口的引流液为血清样或脓性，所取培养物多杀巴斯德菌呈阳性。所有伤口经手术引流和青霉素治疗后均有反应。1例患者发生骨髓炎。猫或狗咬伤后12至24小时手部伤口急性出现蜂窝织炎、淋巴管炎以及血清样或脓性引流液，应提示多杀巴斯德菌为主要病原体。立即手术引流和青霉素治疗是首选治疗方法。
