Shenkman B Z
Vopr Med Khim. 1978 Sep-Oct;24(5):617-20.
Intravenous administration of serotonin into healthy rabbits was accompanied by an increase in content of serotonin in blood of vena cava inferior but the level of serotonin in blood of vena portae and vena centralis hepatis was unaltered. Concentration of serotonin was increased in all parts of the venous system studied after administration of serotonin into andogenous histamine was stimulated. Administration of iproniazid, simultaneously with the dysenteric toxin, led to decrease in inactivation not only of serotonin, but also of histamine.
向健康兔子静脉注射血清素后,下腔静脉血中血清素含量增加,但门静脉和肝中央静脉血中的血清素水平未改变。在注入血清素并刺激内源性组胺后,所研究的静脉系统各部位的血清素浓度均升高。与痢疾毒素同时给予异烟肼,不仅导致血清素失活减少,组胺失活也减少。