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[痢疾中毒时胃肠道和肝脏组织对血清素的灭活作用]

[Serotonin inactivation by tissues of the gastrointestinal tract and liver in the presence of dysenteric poisoning].

作者信息

Shenkman B Z

出版信息

Vopr Med Khim. 1978 Sep-Oct;24(5):617-20.

PMID:706254
Abstract

Intravenous administration of serotonin into healthy rabbits was accompanied by an increase in content of serotonin in blood of vena cava inferior but the level of serotonin in blood of vena portae and vena centralis hepatis was unaltered. Concentration of serotonin was increased in all parts of the venous system studied after administration of serotonin into andogenous histamine was stimulated. Administration of iproniazid, simultaneously with the dysenteric toxin, led to decrease in inactivation not only of serotonin, but also of histamine.

摘要

向健康兔子静脉注射血清素后,下腔静脉血中血清素含量增加,但门静脉和肝中央静脉血中的血清素水平未改变。在注入血清素并刺激内源性组胺后,所研究的静脉系统各部位的血清素浓度均升高。与痢疾毒素同时给予异烟肼,不仅导致血清素失活减少,组胺失活也减少。

相似文献

1
[Serotonin inactivation by tissues of the gastrointestinal tract and liver in the presence of dysenteric poisoning].[痢疾中毒时胃肠道和肝脏组织对血清素的灭活作用]
Vopr Med Khim. 1978 Sep-Oct;24(5):617-20.
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[Analysis of changes in serotonin, histamine, and prostaglandin E2 levels in cerebrospinal fluid and body tissues during hyperthermia of various origins].[不同原因高热期间脑脊液及身体组织中5-羟色胺、组胺和前列腺素E2水平变化分析]
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