Otte J, Emmrich P
Klin Padiatr. 1982 Jan;194(1):18-22. doi: 10.1055/s-2008-1033763.
The incidence of botulism remains high. This disease is burdened by a high lethality rate. It is of significant importance for the patient that therapy is instituted sufficiently early. Botulism is an intoxication with the toxin of Clostridium botulinum. In babies, botulism can be caused also by peroral infection with the bacteria or spores. It appears that intestinal germination to toxin-forming bacteria can occur in babies only. Since honey is very frequently contaminated with Clostridium botulinum spores, honey should be eliminated from baby food. The signs manifested in botulism in infants are similar to those in somewhat older children and adults: increasing muscular hypotonia, apathy, pareses of the cranial nerves, and, finally, respiratory insufficiency through paresis of the respiratory musculature. The authors report on their own observations in cases of botulism, and on current possibilities of treatment.
肉毒中毒的发病率仍然很高。这种疾病因高致死率而负担沉重。对患者来说，尽早开始治疗至关重要。肉毒中毒是由肉毒杆菌毒素引起的中毒。在婴儿中，肉毒中毒也可能由细菌或孢子经口感染引起。似乎只有婴儿会发生肠道内芽孢杆菌萌发形成产毒素细菌的情况。由于蜂蜜经常被肉毒杆菌孢子污染，婴儿食品中应避免使用蜂蜜。婴儿肉毒中毒的表现与稍大儿童及成人的相似：肌肉张力逐渐降低、冷漠、颅神经麻痹，最终因呼吸肌麻痹导致呼吸功能不全。作者报告了他们对肉毒中毒病例的观察结果以及当前的治疗可能性。
