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化脓性脑膜炎后的听力缺陷(作者译)

[Hearing defects after purulent meningitis (author's transl)].

作者信息

Overkamp H, Berg M, Bumm P, Harms D

出版信息

Klin Padiatr. 1982 Jan;194(1):31-4. doi: 10.1055/s-2008-1033766.

Abstract

80 children in the age of 4 to 20 years who got over a purulent meningitis in infancy or childhood were examined by means of several audiological methods. Two children (2,5 percent) were found to be deaf. In 4 cases (5 percent) deafness was detected only unilateral not preferring the right or left ear. Hearing impairment after the eights cranial nerve damage was found in four children. 4 children suffered from severe to profound hearing defects on one side or bilateral. No correlation could be found between incidence and severity of the hearing defects to the total dose of the antibiotics that were penicillin, ampicillin and gentamycin. Before the background of the literature reported on this subject and the presented results hearing impairment after purulent meningitis seems to be more likely a sequela of inflammation than a toxic side-effect of the antibiotics.

摘要

对80名曾在婴儿期或儿童期患过化脓性脑膜炎、年龄在4至20岁的儿童进行了多种听力学检查。发现两名儿童(2.5%)失聪。4例(5%)仅检测到单侧耳聋,无右耳或左耳偏好。4名儿童发现有第八颅神经损伤后的听力障碍。4名儿童一侧或双侧存在重度至极重度听力缺陷。听力缺陷的发生率和严重程度与青霉素、氨苄青霉素和庆大霉素等抗生素的总剂量之间未发现相关性。根据关于该主题的文献报道及呈现的结果,化脓性脑膜炎后的听力障碍似乎更可能是炎症后遗症而非抗生素的毒性副作用。

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