癌症局部热疗的生物学

Med Instrum. 1982 Jan-Feb;16(1):23-6.

Successful cancer therapy must selectively destroy tumor tissue while sparing the host's normal tissues. Local heat treatment can have such a selective effect because abnormalities in tumor blood vessels supply less oxygen to heat-stressed tumor cells and are less efficient in cooling tumor tissue by blood perfusion.

成功的癌症治疗必须在不损伤宿主正常组织的情况下选择性地破坏肿瘤组织。局部热处理可以产生这样的选择性效果，因为肿瘤血管异常，向受热应激的肿瘤细胞供应的氧气较少，并且通过血液灌注冷却肿瘤组织的效率较低。