[Type-C viral particles in cell cultures of chemically induced glioma in Sprague-Dawley rats].

Long-term cultures of a glioma induced in a Sprague-Dawley rat exposed to methylnitrosourea were examined by thin-section electron microscopy. Budding and extracellular lying C-type virus particles were numerous in several samples of the highpassage cultures. This is the first report of a chemically induced rat glioma associated with C-type virus particles. Studies with an aim to characterize this rat glioma associated virus are in progress.