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人睾丸肿瘤(Tera-1)细胞培养中逆转录病毒颗粒的诱导:一项电子显微镜研究。

Induction of retrovirus particles in human testicular tumor (Tera-1) cell cultures: an electron microscopic study.

作者信息

Bronson D L, Fraley E E, Fogh J, Kalter S S

出版信息

J Natl Cancer Inst. 1979 Aug;63(2):337-9.

PMID:287828
Abstract

The Tera-1 and Tera-2 cell lines, established from germ-cell tumors of the human testis, were examined by electron microscopy for particles with the morphology of retroviruses. Extracellular and budding particles were observed at low frequencies only in cultures of Tera-1 cells that had been treated with 5-iodo-2'-deoxyuridine and dexamethasone. No particles were detected in untreated cultures of Tera-1 cells or in any preparations of Tera-2 cells.

摘要

从人睾丸生殖细胞瘤建立的Tera - 1和Tera - 2细胞系,通过电子显微镜检查是否存在具有逆转录病毒形态的颗粒。仅在经5 - 碘 - 2'-脱氧尿苷和地塞米松处理的Tera - 1细胞培养物中,以低频率观察到细胞外颗粒和出芽颗粒。在未处理的Tera - 1细胞培养物或Tera - 2细胞的任何制剂中均未检测到颗粒。

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