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单次被动训练后大鼠海马体和纹状体中的乙酰胆碱代谢

Acetylcholine metabolism in the rat hippocampus and striatum following one-trial passive training.

作者信息

Barker L A, Glick S D, Green J P, Khandelwal J

出版信息

Neuropharmacology. 1982 Feb;21(2):183-5. doi: 10.1016/0028-3908(82)90160-5.

DOI:10.1016/0028-3908(82)90160-5
PMID:7063112
Abstract

The steady state levels of acetylcholine and choline and the synthesis of acetylcholine in the hippocampus and striatum of rat brain have been determined after one-trial passive avoidance training. Steady state levels of acetylcholine and choline were not altered, but the rate of acetylcholine synthesis was significantly elevated in the striatum but not significantly elevated in the hippocampus at one hour after training.

摘要

在单次被动回避训练后,已测定大鼠脑海马体和纹状体中乙酰胆碱和胆碱的稳态水平以及乙酰胆碱的合成。乙酰胆碱和胆碱的稳态水平未发生改变,但训练后1小时,纹状体中乙酰胆碱的合成速率显著升高,而海马体中未显著升高。

相似文献

1
Acetylcholine metabolism in the rat hippocampus and striatum following one-trial passive training.单次被动训练后大鼠海马体和纹状体中的乙酰胆碱代谢
Neuropharmacology. 1982 Feb;21(2):183-5. doi: 10.1016/0028-3908(82)90160-5.
2
Increase in exogenous choline fails to elevate the content or turnover rate of cortical, striatal, or hippocampal acetylcholine.外源性胆碱的增加并不能提高皮质、纹状体或海马体中乙酰胆碱的含量或周转率。
J Neurochem. 1982 Apr;38(4):1160-3. doi: 10.1111/j.1471-4159.1982.tb05364.x.
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The influence of strychnine and glycine on the metabolism of acetylcholine in the rat striatum and hippocampus.士的宁和甘氨酸对大鼠纹状体和海马中乙酰胆碱代谢的影响。
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Effects of aniracetam on one-trial passive avoidance tests and cholinergic neurons in discrete brain regions of rats.阿尼西坦对大鼠单次被动回避试验及离散脑区胆碱能神经元的影响。
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The effect of glycine on acetylcholine metabolism in rat brain.甘氨酸对大鼠脑内乙酰胆碱代谢的影响。
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Effect of oxiracetam and piracetam on central cholinergic mechanisms and active-avoidance acquisition.奥拉西坦和吡拉西坦对中枢胆碱能机制及主动回避学习的影响。
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High affinity choline uptake in striatum and hippocampus: differential effects of treatments which release acetylcholine.纹状体和海马体中的高亲和力胆碱摄取:释放乙酰胆碱的治疗方法的不同作用。
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Levonantradol-induced inhibition of acetylcholine turnover in rat hippocampus and striatum.左诺曲朵对大鼠海马体和纹状体中乙酰胆碱周转的抑制作用。
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