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糖尿病母亲所生孩子的尿糖胺聚糖排泄情况

[Urinary glycosaminoglycan excretion in children born to diabetic mothers].

作者信息

Ignatiuk T E, Ermolenko R I, Semenova E I

出版信息

Probl Endokrinol (Mosk). 1982 Jan-Feb;28(1):14-7.

PMID:7063445
Abstract

Glycosaminoglycan excretion with the urine was determined in 108 children born to mothers suffering from diabetes mellitus. In children with potential and latent diabetes, glycosaminoglycan excretion was increased as compared to children without diabetes mellitus aggravated heredity. The frequency of detection of increased glycosaminoglycan excretion in children did not depend on the length of the disease and its severity in mothers. Glycosaminoglycan excretion with the urine in potential diabetes of children may be regarded as a criterion of the risk of development of microcirculation disturbances of diabetic nature.

摘要

对108名患有糖尿病母亲所生的儿童进行了尿糖胺聚糖排泄量的测定。与无糖尿病且无遗传因素加重的儿童相比,患有潜在性和潜伏性糖尿病的儿童尿糖胺聚糖排泄量增加。儿童中检测到尿糖胺聚糖排泄量增加的频率并不取决于疾病的病程及其在母亲中的严重程度。儿童潜在性糖尿病时的尿糖胺聚糖排泄量可被视为发生糖尿病性微循环障碍风险的一个标准。

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