Siegel M E, Stewart C A, Kwong P, Sakimura I
Radiology. 1982 Apr;143(1):233-5. doi: 10.1148/radiology.143.1.7063732.
Thallium 201 perfusion analysis was compared with Doppler ultrasound as a means of determining the healing potential of an ischemic ulcer of the leg in 27 patients. The degree of hyperemia was determined by comparative point counting of the 201Tl distribution in and about the ulcer. Using established Doppler criteria and a hyperemia ratio greater than 1.5:1, ultrasound alone correctly predicted healing in 15 out of 23 cases and 201Tl in 20 out of 23. Ultrasound correctly predicted non-healing in 3 out of 6 cases, compared with 5 out of 6 for 201Tl. The positive predictive value of the 201Tl study was 63%, versus 27% for ultrasound, and the negative predictive value was 95% for 201Tl and 83% for ultrasound. The accuracy of 201Tl and ultrasound was 86% and 62%, respectively. This limited study suggests that 201Tl perfusion scanning is a useful noninvasive test of ulcer healing potential and may be more sensitive than Doppler ultrasound.
对27例患者的腿部缺血性溃疡愈合潜力评估，比较了铊201灌注分析与多普勒超声检查这两种方法。通过比较溃疡部位及其周围铊201的分布，以点计数法确定充血程度。依据既定的多普勒标准及大于1.5:1的充血比率，仅超声检查在23例中有15例正确预测愈合情况，铊201检查在23例中有20例正确预测。超声检查在6例中有3例正确预测不愈合，铊201检查在6例中有5例正确预测。铊201检查的阳性预测值为63%，超声检查为27%；铊201检查的阴性预测值为95%，超声检查为83%。铊201检查和超声检查的准确率分别为86%和62%。这项有限的研究表明，铊201灌注扫描是评估溃疡愈合潜力的一种有用的非侵入性检查，可能比多普勒超声更敏感。
