Golden E B, Warnock M L, Hulett L D, Churg A M
Am Rev Respir Dis. 1982 Jan;125(1):108-12. doi: 10.1164/arrd.1982.125.1.108.
A laborer who worked in a steel mill and in a shipyard developed a nonspecific pulmonary interstitial fibrosis. Postmortem samples of his lung were digested, and the inorganic material present was extracted and examined using transmission electron microscopy, electron diffraction, and electron microprobe analysis. Uncoated asbestos fibers were present (1.4 X 10(5)/g wet lung), but the surprising finding was the presence of a large number of fly ash particles (6 X 10(6)/g wet lung). Fly ash, the particulate material produced during coal combustion, has not previously been reported to be present in human lung tissue. Although the contribution of the asbestos to this man's lung disease is uncertain, we believe, based on previous studies implicating aluminum silicates in pneumoconiosis, that the fly ash, an aluminum silicate, may be a contributing factor.
一名曾在钢铁厂和造船厂工作的工人患上了非特异性肺间质纤维化。对其肺部的尸检样本进行消化处理，提取其中存在的无机物质，并使用透射电子显微镜、电子衍射和电子微探针分析进行检查。发现了未包覆的石棉纤维（每克湿肺组织中有1.4×10⁵根），但令人惊讶的是还存在大量飞灰颗粒（每克湿肺组织中有6×10⁶个）。飞灰是煤炭燃烧过程中产生的颗粒物质，此前尚未有报道称其存在于人类肺组织中。虽然石棉对该男子肺部疾病的影响尚不确定，但基于先前涉及硅酸盐导致尘肺病的研究，我们认为飞灰这种硅酸盐可能是一个促成因素。
