Ishihara T, Yamazaki S, Kobayashi K, Inoue H, Fukai S, Ito K, Mimura T
Ann Surg. 1982 Apr;195(4):496-500. doi: 10.1097/00000658-198204000-00019.
Twenty-four thyroid carcinoma patients with infiltration of the trachea were treated surgically. The histological diagnosis in these cases included papillary adenocarcinoma in 22 different patients, medullary carcinoma in one patient, and undifferentiated carcinoma in one patient. In 19 of the patients hemoptysis was noted, and dyspnea was present in ten patients. In 14 of the 24 patients the carcinoma was diagnosed by radiographs of the neck, while in seven patients it was demonstrated bronchoscopically. In three patients tracheal infiltration by thyroid carcinoma was diagnosed by biopsy of the tracheal wall at operation. When the tracheal wall was infiltrated by thyroid carcinoma, treatment consisted of circumferential resection of the involved segment of the trachea followed by an end-to-end anastomosis. Of the 24 patients, 17 survived and six died. In the 17 patients who survived, 13 were disease free. Of this number, six survived more than five years after the initial tracheal resection.
24例伴有气管浸润的甲状腺癌患者接受了手术治疗。这些病例的组织学诊断包括22例不同患者为乳头状腺癌,1例为髓样癌,1例为未分化癌。19例患者出现咯血,10例患者存在呼吸困难。24例患者中有14例通过颈部X线片诊断出癌症,7例通过支气管镜检查确诊。3例患者在手术时通过气管壁活检诊断为甲状腺癌气管浸润。当气管壁被甲状腺癌浸润时,治疗包括对受累气管段进行环形切除,然后进行端端吻合。24例患者中,17例存活,6例死亡。在17例存活患者中,13例无疾病。其中,6例在首次气管切除术后存活超过5年。