Rabinovich Ia M, Pinus E A
Biokhimiia. 1982 Jan;47(1):43-6.
The distribution of radioactivity between the growing and finally formed polypeptides in rat liver mitochondria incubated with labelled amino acids was studied. The rate of an "average" polypeptide synthesis in the mitochondrial translation system is much lower than that in bacterial and eukaryotic cytoplasmic protein synthesizing systems. A kinetic study of mitochondrial polypeptide labelling suggests that the rate of ribosomal movement along mRNA in mitochondrial translation systems is variable. It is assumed that the low rate of polypeptide synthesis in mitochondria is due to the delay in ribosome movement along the middle part of mRNA.
研究了用标记氨基酸孵育的大鼠肝线粒体中放射性在生长的和最终形成的多肽之间的分布。线粒体翻译系统中“平均”多肽合成的速率远低于细菌和真核细胞质蛋白质合成系统中的速率。线粒体多肽标记的动力学研究表明，线粒体翻译系统中核糖体沿mRNA移动的速率是可变的。据推测，线粒体中多肽合成速率低是由于核糖体沿mRNA中部移动的延迟所致。
