Smith S R, Connolly J C, Crane P W, Gilmore O J
Br J Surg. 1982 Mar;69(3):153-5. doi: 10.1002/bjs.1800690313.
The effect of surgical drainage materials on rat colonic healing has been investigated in a prospective randomized and controlled study. Latex, silicone rubber (Silastic), polyvinylchloride (PVC) and polytetrafluoroethylene (Teflon) tubes were implanted alongside a colonic anastomosis and compared with a 'no drain' group using mechanical and histological assessments. There was a significant increase in anastomotic leakage in the latex group in which there appears to be a local inhibition of healing. Silastic, PVC and Teflon were not found to interfere with healing. The continued use of latex drains in colonic surgery is therefore questioned.
在一项前瞻性随机对照研究中，对手术引流材料对大鼠结肠愈合的影响进行了调查。将乳胶、硅橡胶（Silastic）、聚氯乙烯（PVC）和聚四氟乙烯（特氟龙）管植入结肠吻合口旁，并与“无引流”组进行机械和组织学评估比较。乳胶组吻合口漏显著增加，似乎存在局部愈合抑制。未发现硅橡胶、PVC和特氟龙干扰愈合。因此，结肠手术中继续使用乳胶引流管受到质疑。
