Lam K, Sefton A J, Bennett M R
Brain Res. 1982 Mar;255(3):487-91. doi: 10.1016/0165-3806(82)90014-1.
The number of axons in the optic nerve of the newborn rat has been compared with the number present in the adult animal. Nerves taken from animals on the day of birth contain 242,000 +/- 29,000 (S.D.) fibres (n = 5). By the sixth postnatal day, the number of axons has fallen to the stable values of adults (99,000 +/- 3700, n = 8). Thus development of the rat's visual system during the first 5 days of life is associated with a loss of 60% of the axons present in the optic nerve at birth. Counts made on the remaining nerve after enucleation of one eye suggest that the presence of retino-retinal axons during the first 5 postnatal days cannot account for all of this reduction.
已将新生大鼠视神经中的轴突数量与成年动物中的轴突数量进行了比较。出生当天取自动物的神经含有242,000±29,000(标准差)条纤维(n = 5)。到出生后第6天,轴突数量已降至成年动物的稳定值(99,000±3700,n = 8)。因此,大鼠视觉系统在出生后前5天的发育与出生时视神经中60%的轴突损失有关。对摘除一只眼睛后剩余神经进行的计数表明,出生后前5天视网膜-视网膜轴突的存在并不能解释所有这种减少。