Muers M F, Faux J A, Ting A, Morris P J
Clin Allergy. 1982 Jan;12(1):47-53. doi: 10.1111/j.1365-2222.1982.tb03125.x.
Twenty-three patients with extrinsic allergic alveolitis due to an allergy to inhaled budgerigar serum protein (budgerigar fancier's lung disease) were typed for HLA-A, B, C and HLA-DR antigens. Antigen frequencies were compared with those found in 154 healthy control subjects. No statistically significant variation in the frequency of any HLA antigen was detected. Exclusion of two patients who had concurrent coeliac disease, and subdivision of the population into those with acute and chronic disease, failed to reveal any significant association with an HLA specificity. A non-significant increase in B8-DR3 amongst the patients with acute disease was noted. Possible reasons for the apparent HLA associations previously reported by others for extrinsic allergic alveolitis are discussed.
对23例因对吸入的虎皮鹦鹉血清蛋白过敏（养鸟人肺疾病）而患外源性过敏性肺泡炎的患者进行了HLA - A、B、C和HLA - DR抗原分型。将抗原频率与154名健康对照者的抗原频率进行了比较。未检测到任何HLA抗原频率有统计学意义的差异。排除两名患有并发乳糜泻的患者，并将人群分为急性和慢性疾病患者，均未发现与HLA特异性有任何显著关联。注意到急性疾病患者中B8 - DR3有非显著性增加。讨论了其他人先前报道的外源性过敏性肺泡炎与HLA明显关联的可能原因。
