Faux J A, Hendrick D J, Anand B S
Clin Allergy. 1978 Mar;8(2):101-8. doi: 10.1111/j.1365-2222.1978.tb00455.x.
Precipitins to avian serum antigens have been found in the sera of bird fanciers and, until now, they have been considered strong supporting evidence for a clinical diagnosis of bird fancier's lung (BFL). We now report that 35% of patients with coeliac disease, none of whom had recently kept a bird, had precipitins against an avian serum antigen common to all the avian species tested, but which was distinct from the antigens usually associated with BFL. This antigen was a component of hen egg yolk but not of bird droppings. In patients with BFL the antibody response results from inhaled antigens in the bird droppings, whereas the antibody response in patients with coeliac disease probably results from eating uncooked or soft-boiled eggs.
养鸟爱好者的血清中发现了针对禽类血清抗原的沉淀素，到目前为止，这些沉淀素一直被视为鸟类饲养者肺（BFL）临床诊断的有力支持证据。我们现在报告，35%的乳糜泻患者（其中没有一人近期养过鸟）对所有测试禽类物种共有的一种禽类血清抗原产生了沉淀素，但该抗原与通常与BFL相关的抗原不同。这种抗原是鸡蛋黄的一种成分，而非鸟粪的成分。在BFL患者中，抗体反应是由吸入鸟粪中的抗原引起的，而乳糜泻患者的抗体反应可能是由于食用未煮熟或半熟的鸡蛋所致。
