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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Perret G, Bladier D, Vassy R, Cornillot P

Comp Biochem Physiol B. 1982;71(3):545-8. doi: 10.1016/0305-0491(82)90427-8.

In distinction to mammalian erythrocytes, splitting of sialic acids of non-mammalian erythrocytes (chicken and newt) by Vibrio cholerae neuraminidase (VCN) does not lead to a dramatic decrease in their viability. 2. One of the possibilities to explain this discrepancy is the ability of chicken and newt desialosylated erythrocytes to repair the enzymatic injury. 3. To test this hypothesis we used the property of peanut agglutinin (PNA) to agglutinate desialosylated erythrocytes. 4. Desialosylated erythrocytes of all the species tested remain PNA-agglutinable throughout their whole life time in the blood stream. The absence of effect of VCN on chicken and newt erythrocytes is therefore not due to their resialosylation.

与哺乳动物红细胞不同，霍乱弧菌神经氨酸酶（VCN）对非哺乳动物红细胞（鸡和蝾螈）唾液酸的裂解不会导致其活力急剧下降。2. 解释这种差异的一种可能性是鸡和蝾螈去唾液酸化红细胞修复酶损伤的能力。3. 为了验证这一假设，我们利用花生凝集素（PNA）凝集去唾液酸化红细胞的特性。4. 所有测试物种的去唾液酸化红细胞在其血流中的整个生命周期内都保持可被PNA凝集。因此，VCN对鸡和蝾螈红细胞没有影响并非由于它们的再唾液酸化。

Perret G, Bladier D, Vassy R, Cornillot P

Comp Biochem Physiol B. 1982;71(3):545-8. doi: 10.1016/0305-0491(82)90427-8.

In distinction to mammalian erythrocytes, splitting of sialic acids of non-mammalian erythrocytes (chicken and newt) by Vibrio cholerae neuraminidase (VCN) does not lead to a dramatic decrease in their viability. 2. One of the possibilities to explain this discrepancy is the ability of chicken and newt desialosylated erythrocytes to repair the enzymatic injury. 3. To test this hypothesis we used the property of peanut agglutinin (PNA) to agglutinate desialosylated erythrocytes. 4. Desialosylated erythrocytes of all the species tested remain PNA-agglutinable throughout their whole life time in the blood stream. The absence of effect of VCN on chicken and newt erythrocytes is therefore not due to their resialosylation.

与哺乳动物红细胞不同，霍乱弧菌神经氨酸酶（VCN）对非哺乳动物红细胞（鸡和蝾螈）唾液酸的裂解不会导致其活力急剧下降。2. 解释这种差异的一种可能性是鸡和蝾螈去唾液酸化红细胞修复酶损伤的能力。3. 为了验证这一假设，我们利用花生凝集素（PNA）凝集去唾液酸化红细胞的特性。4. 所有测试物种的去唾液酸化红细胞在其血流中的整个生命周期内都保持可被PNA凝集。因此，VCN对鸡和蝾螈红细胞没有影响并非由于它们的再唾液酸化。