Dushanin S A, Pirogova E A
Cor Vasa. 1982;24(1):27-57.
The effectivity of subendocardial perfusion was investigated in 266 probands aged 40-68 years (112 patients with ischaemic heart disease, 116 patients with essential hypertension, and 38 practically healthy persons) by a noninvasive technique - the myocardial vitality index (MVI) or the quotient of the diastolic and systolic tension-time indexes (DTTI/STTI). The close and statistically significant correlation was found between the MVI, findings of selective coronarography, and total physical performance (exercise tolerance threshold) in per cent of the maximal oxygen consumption (MOC) adequate to the given subject's age, sex, and body mass. Attention is drawn to the diagnostic potential of the novel mode of a rapid assessment of the expected exercise tolerance threshold in per cent of the admissible MOC, determined by the magnitude of the coronary reserved of energy output (in kcal/min or kJ/min), and to the possibilities of predicting the maximal admissible heart rate during exercise on the basis of the myocardial oxygen supply/consumption quotient during a state of relative muscular rest, reflecting the MVI.
采用无创技术——心肌活力指数（MVI）或舒张期与收缩期张力 - 时间指数之比（DTTI/STTI），对266名年龄在40 - 68岁的受试者（112例缺血性心脏病患者、116例原发性高血压患者和38名实际健康者）的心内膜下灌注有效性进行了研究。研究发现，MVI、选择性冠状动脉造影结果与以最大耗氧量（MOC）百分比表示的总体能（运动耐力阈值）之间存在密切且具有统计学意义的相关性，该最大耗氧量百分比是根据受试者的年龄、性别和体重确定的。文中还提到了一种新的评估预期运动耐力阈值的方法的诊断潜力，该方法以可接受的MOC百分比来表示，由冠状动脉能量输出储备量（以千卡/分钟或千焦/分钟为单位）确定；同时还提到了基于相对肌肉休息状态下反映MVI的心肌氧供/氧耗商来预测运动期间最大可接受心率的可能性。
