3T3-L1脂肪细胞中胰岛素受体潜伏池的鉴定与表征。 - Suppr

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超能文献

Identification and characterization of a latent pool of insulin receptors in 3T3-L1 adipocytes.

作者信息

Deutsch P J, Rosen O M, Rubin C S

出版信息

J Biol Chem. 1982 May 25;257(10):5350-8.

PMID:7068595

Abstract

摘要

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Identification and characterization of a latent pool of insulin receptors in 3T3-L1 adipocytes.3T3-L1脂肪细胞中胰岛素受体潜伏池的鉴定与表征。

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Biogenesis, transit, and functional properties of the insulin proreceptor and modified insulin receptors in 3T3-L1 adipocytes. Use of monensin to probe proreceptor cleavage and generate altered receptor subunits.3T3-L1脂肪细胞中胰岛素原受体和修饰胰岛素受体的生物发生、转运及功能特性。使用莫能菌素探究原受体裂解并生成改变的受体亚基。

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Direct comparison of the rates of internalization and degradation of covalent receptor-insulin complexes in 3T3-L1 adipocytes. Internalization of occupied receptors is not the rate-limiting step in receptor-hormone complex degradation.3T3-L1脂肪细胞中共价受体-胰岛素复合物内化率与降解率的直接比较。被占据受体的内化并非受体-激素复合物降解的限速步骤。

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Latent insulin receptors and possible receptor precursors in 3T3-L1 adipocytes.3T3-L1脂肪细胞中的潜在胰岛素受体及可能的受体前体

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Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta.胰岛素可激活3T3-L1脂肪细胞和人胎盘提取物中的一种酪氨酸特异性蛋白激酶。

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Growth hormone and insulin-like growth factors I and II produce distinct alterations in glucose metabolism in 3T3-F442A adipocytes.生长激素以及胰岛素样生长因子I和II在3T3-F442A脂肪细胞中对葡萄糖代谢产生不同的改变。

Proc Natl Acad Sci U S A. 1985 Dec;82(24):8724-8. doi: 10.1073/pnas.82.24.8724.

Purification of the colony-stimulating factor 1 receptor and demonstration of its tyrosine kinase activity.集落刺激因子1受体的纯化及其酪氨酸激酶活性的证明。

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Presence of insulin receptors in cultured glial C6 cells. Regulation by butyrate.培养的神经胶质C6细胞中胰岛素受体的存在。丁酸盐的调节作用。

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Intracellular pools of transferrin receptors result from constitutive internalization of unoccupied receptors.转铁蛋白受体的细胞内池源自未被占据的受体的组成型内化。

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Phenylarsine oxide-induced increase in alveolar macrophage surface receptors: evidence for fusion of internal receptor pools with the cell surface.苯胂化氧诱导肺泡巨噬细胞表面受体增加：内部受体池与细胞表面融合的证据。

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