Marshall J
J Neurol Sci. 1982 Mar;53(3):473-8. doi: 10.1016/0022-510x(82)90244-1.
A study of 192 personal cases of completed stroke, reversible ischaemic neurological deficit (RIND) or transient ischaemic attack (TIA) in patients aged 10-49 years seen between 1961 ad 1979 inclusive is reported. Three died acutely; 189 were followed for up to 15 years. The main cause of the initial event was atheromatous or hypertensive vascular disease. Of the 90 patients whose initial event was a completed stroke 19(21%) developed a second stroke, whereas only 4 of the 78 patients with TIA suffered a stroke later. In the entire series there were 6 cardiac deaths and one from mesenteric thrombosis during the follow-up period. The risk of stroke following TIA is less in persons under 50 years than in the older age group. The risk of a second stroke following an initial stroke depends on whether or not there is evidence of vascular disease. In the absence of such evidence the risk is small; in the presence of evidence it is high, being of the order of 20%.
报告了一项对1961年至1979年（含）期间就诊的10至49岁患者中192例完全性卒中、可逆性缺血性神经功能缺损（RIND）或短暂性脑缺血发作（TIA）个人病例的研究。3例急性死亡；189例随访长达15年。初始事件的主要原因是动脉粥样硬化或高血压性血管疾病。在90例初始事件为完全性卒中的患者中，19例（21%）发生了第二次卒中，而78例TIA患者中只有4例后来发生了卒中。在整个系列中，随访期间有6例心源性死亡和1例肠系膜血栓形成死亡。50岁以下人群TIA后发生卒中的风险低于老年组。首次卒中后发生第二次卒中的风险取决于是否有血管疾病的证据。在没有此类证据的情况下，风险较小；在有证据的情况下，风险较高，约为20%。
