Yokoyama M, Watanabe K, Inatsuki S, Ochi K, Takeuchi M
J Urol. 1982 Apr;127(4):721-3. doi: 10.1016/s0022-5347(17)54016-1.
Computerized tomography can be used not only for morphological studies but for physiological ones as well. Using computerized tomography, we were able to observe changes in renal parenchymal flow rates, with the aorta and renal parenchyma as regions of interest. There were 62 studies performed on 48 patients with and without known renal disease. The change in the tissue-plasma ratio with the use of contrast medium in 124 renal units correlated well with the renal function observed on excretory urography. The 14 patients subjected to renal ischemia during surgery underwent computerized tomography before and after the operation. The change in the tissue-plasma ratio of those kidneys operated upon was decreased significantly postoperatively compared to values found for the nonischemic contralateral kidneys. The results were reproducible and suggest that computerized tomography can be used as a method of evaluating the renal function per unit of parenchymal volume.
计算机断层扫描不仅可用于形态学研究，也可用于生理学研究。通过计算机断层扫描，我们能够观察肾实质血流速率的变化，将主动脉和肾实质作为感兴趣区域。对48例已知或未知肾病的患者进行了62项研究。124个肾单位使用造影剂后组织 - 血浆比值的变化与排泄性尿路造影观察到的肾功能密切相关。14例在手术期间经历肾缺血的患者在手术前后接受了计算机断层扫描。与未缺血的对侧肾脏相比，接受手术的肾脏术后组织 - 血浆比值的变化显著降低。结果具有可重复性，表明计算机断层扫描可用作评估每单位实质体积肾功能的一种方法。
