Killip T h
Kardiologiia. 1982 Feb;22(2):33-7.
Visualization of the lumen of the coronary arteries by angiography has greatly expanded the ability of the physician to evaluate the extent of disease in patients suspected of having an ischaemic cardiac disorder. Criteria for coronary angiography have been developed in part by reviewing the experience in the Coronary Artery Surgery Study, CASS. During a five year period at 15 participating sites 24959 consecutive patients undergoing angiography for suspicion of coronary artery disease were enrolled. Chest pain was the dominant symptom in more than 80%. Unstable angina occurred in more than 1/3 of patients classified as definite or probably angina pectoris. The majority of patients were in Canadian Class 2,3. In a study previous reported by CASS a mortality of 002 and a morbidity (myocardial infarction) of 003 was found; presence of left main disease increased mortality 6.8 times. In males, 79% had significant and 12% no CAD; left main disease occurred in 9%. In females 45% had significant and 40% no CAD; left main disease occurred in 4%. The distribution of 1,2 and 3 vessel disease will be presented. From these data and a survey of clinical experience during the past several years, 10 indications for visualization of the coronary artery anatomy by angiography have been developed. These indications are presented for discussion.
通过血管造影术对冠状动脉管腔进行可视化,极大地扩展了医生评估疑似患有缺血性心脏病患者疾病程度的能力。冠状动脉造影的标准部分是通过回顾冠状动脉外科手术研究(CASS)的经验制定的。在五年期间,15个参与地点连续纳入了24959名因疑似冠状动脉疾病而接受血管造影的患者。胸痛是超过80%患者的主要症状。在被归类为明确或可能心绞痛的患者中,超过1/3发生不稳定型心绞痛。大多数患者属于加拿大心血管学会分级2、3级。在CASS先前报告的一项研究中,发现死亡率为0.02,发病率(心肌梗死)为0.03;左主干病变使死亡率增加6.8倍。在男性中,79%有显著冠状动脉疾病,12%没有;左主干病变发生率为9%。在女性中,45%有显著冠状动脉疾病,40%没有;左主干病变发生率为4%。将展示单支、双支和三支血管病变的分布情况。根据这些数据以及对过去几年临床经验的调查,已制定了10条通过血管造影术可视化冠状动脉解剖结构的指征。现列出这些指征以供讨论。