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在百草枯中毒方面,活性炭与漂白土或膨润土的效果相同。

Activated charcoal is as effective as fuller's earth or bentonite in paraquat poisoning.

作者信息

Okonek S, Setyadharma H, Borchert A, Krienke E G

出版信息

Klin Wochenschr. 1982 Feb 15;60(4):207-10. doi: 10.1007/BF01715588.

DOI:10.1007/BF01715588
PMID:7070010
Abstract

In vitro investigations have shown that the adsorption capacity of activated charcoal ('Kohle-Compretten', 'Ultracarbon', E. Merck, Darmstadt, FRG) is just as high as that of 'Fuller's earth' (Surrey powder, Laporte Industries Ltd., Luton, GB) or 'Bentonite BP W.B. (Steetley Minerals Ltd., Milton Keynes, GB). Fuller's earth ('Fullererde') from another manufacturer has had very poor adsorption properties and is thus not suitable for the treatment of paraquat poisoning. Animal experiments have shown that the curative effect of activated charcoal given 0.5, 1, 2, and 3 h after ingestion of 200 and 300 mg paraquat/kg body weight is equally as good or even better than that of 'Fuller's earth' or 'Bentonite BP W.B' Activated charcoal is a substitute of equal value to these mineral soils.

摘要

体外研究表明,活性炭(“Kohle-Compretten”、“Ultracarbon”,德国默克公司,达姆施塔特,联邦德国)的吸附能力与“漂白土”(萨里粉,拉波特工业有限公司,卢顿,英国)或“膨润土BP W.B.”(斯特利矿物有限公司,米尔顿凯恩斯,英国)一样高。另一家制造商生产的“漂白土”(“Fullererde”)吸附性能很差,因此不适用于百草枯中毒的治疗。动物实验表明,在摄入200和300毫克百草枯/千克体重后0.5、1、2和3小时给予活性炭,其治疗效果与“漂白土”或“膨润土BP W.B.”相当,甚至更好。活性炭是这些矿物土壤的等效替代品。

相似文献

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Activated charcoal is as effective as fuller's earth or bentonite in paraquat poisoning.在百草枯中毒方面,活性炭与漂白土或膨润土的效果相同。
Klin Wochenschr. 1982 Feb 15;60(4):207-10. doi: 10.1007/BF01715588.
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2
The use of biochar in animal feeding.生物炭在动物饲养中的应用。
PeerJ. 2019 Jul 31;7:e7373. doi: 10.7717/peerj.7373. eCollection 2019.
3
Bentonite Clay as a Natural Remedy: A Brief Review.膨润土作为一种天然疗法:简要综述。

本文引用的文献

1
An economical hemoperfusion system to determine in vitro clearances of various poisons with different adsorbents.
Arch Toxicol. 1980 Dec;46(3-4):215-20. doi: 10.1007/BF00310437.
2
Absorption and excretion of diquat and paraquat in rats.大鼠体内敌草快和百草枯的吸收与排泄
Br J Ind Med. 1966 Apr;23(2):133-6. doi: 10.1136/oem.23.2.133.
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Inhibition of the absorption of paraquat from the gastrointestinal tract by adsorbents.吸附剂对百草枯胃肠道吸收的抑制作用。
Br J Ind Med. 1971 Apr;28(2):186-8. doi: 10.1136/oem.28.2.186.
Iran J Public Health. 2017 Sep;46(9):1176-1183.
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Effect of DMPS and various adsorbents on the arsenic excretion in guinea-pigs after injection with As2O3.二巯基丙磺酸钠(DMPS)及各种吸附剂对注射三氧化二砷后豚鼠砷排泄的影响。
Arch Toxicol. 1995;69(10):712-7. doi: 10.1007/s002040050237.
5
Clinical pharmacokinetics of oral activated charcoal in acute intoxications.口服活性炭在急性中毒中的临床药代动力学
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6
Oral activated charcoal in the treatment of intoxications. Role of single and repeated doses.口服活性炭治疗中毒。单次和重复剂量的作用。
Med Toxicol Adverse Drug Exp. 1988 Jan-Dec;3(1):33-58. doi: 10.1007/BF03259930.
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The changing pattern of paraquat poisoning: an epidemiologic study.百草枯中毒模式的变化:一项流行病学研究。
Ir Med J. 1978 Mar 18;71(4):103-8.
5
Two survivors of severe paraquat intoxication by "continuous hemoperfusion".两名严重百草枯中毒患者经“持续血液灌流”治疗后存活。
Klin Wochenschr. 1979 Sep 17;57(18):957-9. doi: 10.1007/BF01478553.
6
Paraquat poisoning: a review.百草枯中毒:综述
Am J Hosp Pharm. 1978 Nov;35(11):1368-72.
7
Paraquat poisoning: significance of plasma-paraquat concentrations.百草枯中毒:血浆百草枯浓度的意义
Lancet. 1979 Aug 18;2(8138):330-2. doi: 10.1016/s0140-6736(79)90345-3.