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吸附剂对百草枯胃肠道吸收的抑制作用。

Inhibition of the absorption of paraquat from the gastrointestinal tract by adsorbents.

作者信息

Clark D G

出版信息

Br J Ind Med. 1971 Apr;28(2):186-8. doi: 10.1136/oem.28.2.186.

Abstract

186-188. The efficacy of the oral administration of adsorbents Kaolin, Decalso, Amberlite, Bentonite and Fuller's Earth in preventing the toxic actions of ingested paraquat (1,1'-dimethyl-4,4'-dipyridylium) has been assessed using rats and cats. Only Bentonite and Fuller's Earth were found to have any effect, and they were both more effective than a simple stomach wash. It is suggested that these materials may be useful as immediate antidotes to paraquat poisoning in man. Fuller's Earth is preferable to Bentonite as it can be used as a more concentrated suspension, leading to a beneficial reduction in therapeutic volume.

摘要

186 - 188. 已使用大鼠和猫评估了口服吸附剂高岭土、Decalso、 Amberlite、膨润土和漂白土预防摄入百草枯(1,1'-二甲基-4,4'-联吡啶)毒性作用的效果。仅发现膨润土和漂白土有任何效果,且它们都比单纯洗胃更有效。建议这些物质可作为人类百草枯中毒的即时解毒剂。漂白土比膨润土更可取,因为它可以制成更浓缩的悬浮液,从而有益地减少治疗量。

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引用本文的文献

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3
The toxicity of paraquat.百草枯的毒性。
Br J Ind Med. 1966 Apr;23(2):126-32. doi: 10.1136/oem.23.2.126.
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Paraquat poisoning treated by forced diuresis.采用强制利尿法治疗百草枯中毒。
Br Med J. 1968 Aug 3;3(5613):290-1. doi: 10.1136/bmj.3.5613.290.
6
Acute renal failure in case of Paraquat poisoning.百草枯中毒所致急性肾衰竭
Br Med J. 1968 Mar 23;1(5594):749-50. doi: 10.1136/bmj.1.5594.749.

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