Santavirta S, Höckerstedt K, Niinikoski J
Acta Orthop Scand. 1978 Oct;49(5):451-9.
Recent investigations suggest that circulation in a limb can be reduced with a tourniquet to less than 1 per cent of the control limb, or even completely occluded. The development of tissue oxygen tonometry with implanted silastic tubes has provided new possibilities for assessing muscle tissue oxygen tension. In the present work, this method was employed to register the effect of tourniquet blackade on the lower limb muscle PO2 in rabbits. The duration of the tourniquet blockade was 60, 120 and 180 minutes. The baseline muscle PO2 in the tibialis anterior muscle was 22.6 +/- 0.6 mmHg. During the tourniquet blockade the oxygen tension dropped to minimal values between 9.2 +/- 0.5 and 10.7 +/- 0.6 mmHg in these experimental groups, but the tissue microclimate never reached fully anoxic conditions. The rapid response of muscle PO2 to oxygen breathing after release of the blockade suggests that limb microcirculation tolerates tourniquet occlusion well.
最近的研究表明,使用止血带可使肢体循环减少至对照肢体的1%以下,甚至完全阻断。植入硅橡胶管的组织氧张力测定法的发展为评估肌肉组织氧张力提供了新的可能性。在本研究中,采用该方法记录止血带阻断对兔下肢肌肉PO2的影响。止血带阻断的持续时间为60、120和180分钟。胫前肌的基线肌肉PO2为22.6±0.6 mmHg。在止血带阻断期间,这些实验组的氧张力降至9.2±0.5至10.7±0.6 mmHg之间的最小值,但组织微环境从未达到完全缺氧状态。阻断解除后肌肉PO2对吸氧的快速反应表明肢体微循环对止血带阻断耐受性良好。