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[止血带休克时不同器官和组织的氧张力及血流动力学指标]

[Oxygen tension in different organs and tissues and hemodynamic indices during tourniquet shock].

作者信息

Myslovatyĭ B S, Zairov D K, Chebotarev A A, Muzykantskiĭ E L

出版信息

Biull Eksp Biol Med. 1982 Jul;94(7):19-22.

PMID:7126816
Abstract

Experiments were made on 160 rats to examine the time course of changes in oxygen tension (pO2) in different organs and tissues during tourniquet shock. It was ascertained that pO2 in the liver was reduced before the tourniquets were removed from the limbs, in the presence of normal characteristics of the central and systemic hemodynamics. After circulation in the limbs was resumed following 6 hours of ischemia, pO2 in the liver and kidneys was reduced, respectively, to 26.8 and 48.6% of normal for 4 hours. It was disclosed that these changes preceded the shifts in circulation. pO2 in the small intestine, skin and muscles also fell to 97, 80.8 and 79.4%, respectively, within the same period of time. Oxygen tension in the cerebral cortex remained high within all the periods of tourniquet shock. pO2 fall in the cerebral cortex was seen only in the agonal period in the presence of deep disorders in circulation and respiration.

摘要

对160只大鼠进行了实验,以研究在止血带休克期间不同器官和组织中氧分压(pO2)的变化时间过程。已确定,在肢体止血带未解除之前,肝脏中的pO2就已降低,此时中央和全身血流动力学特征正常。在肢体缺血6小时后恢复循环后,肝脏和肾脏中的pO2分别在4小时内降至正常水平的26.8%和48.6%。结果表明,这些变化先于循环的改变。在同一时间段内,小肠、皮肤和肌肉中的pO2也分别降至97%、80.8%和79.4%。在止血带休克的所有阶段,大脑皮质中的氧分压均保持较高水平。仅在濒死期,当循环和呼吸出现严重紊乱时,才会观察到大脑皮质中的pO2下降。

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