Eliseo V, Bettiga R, Giordano A, Iaccarino P, Perez G, Romeo D, Scotto G, Stornaiuolo A
Minerva Med. 1982 Apr 2;73(14):829-34.
An assessment was made of the fourth heart sound as a non-invasive clinical and instrumental aid in the diagnosis of latent cardiac insufficiency. The sound was recorded in various decubitus positions in a series of healthy subjects and patients with recent and past infarction, under basal conditions, after exercise on the cycle ergometer, and after digitalis i.v. Persistence of the fourth sound in the standing position was noted in nearly all infarct patients, while its incidence decreased significantly after digitalis. It is felt that this finding can be interpreted as evidence of the non-existence of latent heart failure. Its further investigation and correlation with other invasive and non-invasive instrumental examinations is proposed.
对第四心音作为诊断潜在心功能不全的一种非侵入性临床和器械辅助手段进行了评估。在一系列健康受试者以及近期和既往有心肌梗死的患者中，于不同卧位记录该心音，记录条件包括基础状态、在蹬车测力计上运动后以及静脉注射洋地黄后。几乎所有心肌梗死患者在站立位时第四心音持续存在，而在使用洋地黄后其发生率显著降低。有人认为这一发现可被解释为不存在潜在心力衰竭的证据。建议对其进一步研究并与其他侵入性和非侵入性器械检查进行关联分析。
