Guggenheim B, Ben-Zur E
Schweiz Med Wochenschr. 1982 Feb 13;112(7):232-4.
Occasional clinical observations have shown extensive caries lesions in small children between 12 and 36 months of age, in some of which cases, while sugar intake history was negative, continuous use of teething jellies, lozenges or syrups was established. This prompted the hypothesis that such products were the source of the hidden fermentable sugars, and the sugar content of a number of products available on the Swiss market was therefore analyzed. Sucrose was determined enzymatically using the Boehringer sucrose/glucose UV-test. The content of other fermentable carbohydrates was checked by GLC. The use of such products should not be recommended for real or assumed pain related to the eruption of primary teeth. Among the eight products tested only one was found to be free of fermentable sugars. All other preparations contained 31-93% fermentable sugars, chiefly sucrose. Declaration of fermentable sugars in such products should be enforced by food and drug legislation.
偶尔的临床观察发现，12至36个月大的幼儿中存在广泛的龋齿病变，在其中一些病例中，虽然糖分摄入史为阴性，但确定他们持续使用了出牙凝胶、含片或糖浆。这促使人们提出这样的假设，即此类产品是隐藏的可发酵糖的来源，因此对瑞士市场上一些此类产品的含糖量进行了分析。使用勃林格蔗糖/葡萄糖紫外线测试法通过酶法测定蔗糖含量。通过气相色谱法检查其他可发酵碳水化合物的含量。对于与乳牙萌出相关的实际或假定疼痛，不应推荐使用此类产品。在所测试的八种产品中，仅发现一种不含可发酵糖。所有其他制剂含有31%至93%的可发酵糖，主要是蔗糖。此类产品中可发酵糖的标注应通过食品和药物立法来强制实施。
