Graham K, Caird F I
Age Ageing. 1978 Aug;7(3):146-50. doi: 10.1093/ageing/7.3.146.
Twenty elderly patients with intracranial tumour were treated with high-dose steroids (beta- or dexamethasone 12--16 mg per day). Six of eight patients with primary intracranial malignancies and four of six with metastatic tumours showed a definite response of conscious level and/or neurological deficit. One of two patients with lymphoma responded but neither of two with meningioma. Six patients were able to return home. Two patients suffered serious, and three minor, side-effects attributable to steroid therapy, but this treatment has a definite place in the management of intracranial tumour in old age.
20例老年颅内肿瘤患者接受了大剂量类固醇治疗（β-米松或地塞米松，每日12 - 16毫克）。8例原发性颅内恶性肿瘤患者中有6例，6例转移性肿瘤患者中有4例在意识水平和/或神经功能缺损方面有明确改善。2例淋巴瘤患者中有1例有反应，但2例脑膜瘤患者均无反应。6例患者能够回家。2例患者出现了严重的类固醇治疗副作用，3例出现轻微副作用，但这种治疗在老年颅内肿瘤的治疗中确有一席之地。
