Oonishi T, Ishiko T, Arai M, Kase M, Matsushita M
Acta Pathol Jpn. 1982 Jan;32(1):163-71. doi: 10.1111/j.1440-1827.1982.tb02038.x.
Presented here is an autopsy case of pachymeningitis cervicalis hypertrophica. A 77-year-old female had the initial symptoms of cervical radiculopathy which terminated in the syndrome of spinal cord transection. Prior to the onset of radiculopathy, the patient had been admitted to the hospital because of a fever and had been shown to have granulomatous sinusitis. Autopsy revealed chronic granulomatous pachymeningitis of the cervical spinal cord, the lesion being mostly restricted to this region. From histopathologic similarities, the extension of sinusitis to cervical pachymeningitis was assumed, but this was not confirmed. An attempt to discover the causative micro-organisms was unsuccessful. The possibility of a limited form of Wegener's granulomatosis could be excluded in view of the absence of true angiitis. Corresponding to the levels of pachymeningitis, the spinal cord was also severely damaged, which was principally due to circulatory disturbance as a result of pachymeningitis.
本文介绍了一例肥厚性颈硬脊膜炎的尸检病例。一名77岁女性最初出现颈神经根病症状，最终发展为脊髓横断综合征。在神经根病发作之前，患者因发热入院，检查发现患有肉芽肿性鼻窦炎。尸检显示颈段脊髓存在慢性肉芽肿性硬脊膜炎，病变主要局限于该区域。从组织病理学相似性推测，鼻窦炎蔓延至颈段硬脊膜炎，但未得到证实。试图发现致病微生物未成功。鉴于无真正的血管炎，可排除局限性韦格纳肉芽肿病的可能性。与硬脊膜炎的节段相对应，脊髓也受到严重损伤，这主要是由于硬脊膜炎导致的循环障碍。
