Ingeberg S, Deding A, Jensen M K
Acta Med Scand. 1982;211(1-2):19-21. doi: 10.1111/j.0954-6820.1982.tb01895.x.
Bone mineral content (BMC) was determined by photon absorptiometry on both forearms in 28 patients with myelomatosis. Nineteen patients had received intermittent treatment with cytostatic agents and prednisone. No significant reduction of BMC was found between the patients with myelomatosis and an age- and sex-matched normal population. Neither was any significant decrease in BMC with the duration of the disease demonstrated. In 16 patients, routine X-ray indicated osteoporosis, but their BMC was not reduced compared to the patients without osteoporosis on X-ray. However, the former patients were significantly older than the latter. Provided the term "generalized osteoporosis" implies reduced mineral content in all bones, the study indicates that patients with myelomatosis have not generalized osteoporosis.
采用光子吸收法测定了28例骨髓瘤患者双侧前臂的骨矿物质含量（BMC）。19例患者接受了细胞抑制剂和泼尼松的间歇治疗。骨髓瘤患者与年龄和性别匹配的正常人群相比，未发现BMC有显著降低。疾病持续时间与BMC也未显示出任何显著下降。16例患者的常规X线检查显示有骨质疏松，但与X线检查无骨质疏松的患者相比，其BMC并未降低。然而，前者患者的年龄明显大于后者。如果“全身性骨质疏松”一词意味着所有骨骼中的矿物质含量降低，那么该研究表明骨髓瘤患者不存在全身性骨质疏松。
