变应性嗜酸性胃肠结肠炎中的播散性溃疡

Disseminated ulcerations in allergic eosinophilic gastroenterocolitis.

作者信息

Lucak B K, Sansaricq C, Snyderman S E, Greco M A, Fazzini E P, Bazaz G R

出版信息

Am J Gastroenterol. 1982 Apr;77(4):248-52.

Abstract

An infant with allergic eosinophilic gastroenterocolitis is described. The patient presented with vomiting, diarrhea, gastrointestinal bleeding, and failure to thrive. Anemia, hypoproteinemia, and peripheral eosinophilia were also present. Gastrointestinal endoscopy revealed multiple mucosal ulcerations in the stomach, small intestine, and colon. Histological study of the affected areas showed infiltration of the mucosa by eosinophils, increased mucosal IgE plasma cells, and activated intraepithelial lymphocytes. Treatment with corticosteroids resulted in clinical and histological remission.

摘要

本文描述了一名患有过敏性嗜酸性胃肠结肠炎的婴儿。该患者出现呕吐、腹泻、胃肠道出血及发育不良。同时存在贫血、低蛋白血症及外周血嗜酸性粒细胞增多。胃肠内镜检查显示胃、小肠和结肠有多处黏膜溃疡。对受累区域的组织学研究显示黏膜有嗜酸性粒细胞浸润、黏膜IgE浆细胞增多及上皮内淋巴细胞活化。使用皮质类固醇治疗后临床及组织学症状缓解。