Daubs J
Am J Optom Physiol Opt. 1982 Mar;59(3):271-7. doi: 10.1097/00006324-198203000-00012.
Malignant myopia is a major cause of blindness, yet compared with cataract, glaucoma, or diabetic retinopathy, this condition has received little attention from clinical investigators. This study explores existing health and geophysical records in search of clues that might suggest directions for further research into the etiology of blinding myopia. From the environmental data available for analysis, annual hours of sunshine emerged as the factor with the strongest (inverse) association with malignant myopia. Using data from the 14-state Model Reporting Area for Blindness, a case-referent study of this factor revealed both sex and age-birth year modifications of this effect. Relatively more blindness due to malignant myopia occurred among women in low sunshine regions and among men in high sunshine regions. The effect among women appeared during middle age (45 +, or born before 1926) but among men was not seen until later (age 65 + or born before 1906).
恶性近视是失明的一个主要原因，然而与白内障、青光眼或糖尿病性视网膜病变相比，这种病症很少受到临床研究人员的关注。本研究探索现有的健康和地球物理记录，以寻找可能为进一步研究致盲性近视的病因指明方向的线索。从可用于分析的环境数据中，年日照时长成为与恶性近视关联最强（呈负相关）的因素。利用来自14个州失明模型报告地区的数据，对这一因素进行的病例对照研究揭示了这种效应在性别和年龄-出生年份方面的差异。在日照较少地区的女性以及日照较多地区的男性中，因恶性近视导致的失明相对更多。女性中的这种效应出现在中年时期（45岁及以上，或出生于1926年之前），而男性中的这种效应直到更晚才出现（65岁及以上，或出生于1906年之前）。
