Daubs J G
Ophthalmic Physiol Opt. 1984;4(2):143-9.
From an exploratory study of the population of 16 states in the Model Reporting Area for Blindness in the U.S. the incidence rate of reported blindness due to malignant myopia was found to be inversely related to distance to seacoast (r = -0.67) and with certain correlates of this distance; sunshine (r = -0.67), fluoride (r = -0.18 - -0.77), calcium (r = -0.66), and selenium (r = -0.68). These findings are similar to those for dental caries, except for selenium which is said to increase caries. Although these findings are analogous, do demonstrate an effect gradient, and are not biologically implausible , replication under less confounded conditions should precede a quantitative statement of causality.
通过对美国失明模型报告区16个州的人口进行的一项探索性研究,发现因恶性近视导致的失明报告发病率与到海岸的距离呈负相关(r = -0.67),且与该距离的某些相关因素有关;阳光(r = -0.67)、氟化物(r = -0.18至-0.77)、钙(r = -0.66)和硒(r = -0.68)。这些发现与龋齿的发现相似,除了据说会增加龋齿的硒。尽管这些发现具有相似性,确实显示出效应梯度,且在生物学上并非不合理,但在进行因果关系的定量陈述之前,应在干扰较少的条件下进行重复研究。