Sequeira W, Jones E, Siegel M E, Lorenz M, Kallick C
Ann Intern Med. 1982 May;96(5):604-6. doi: 10.7326/0003-4819-96-5-604.
Four cases of Pseudomonas aeruginosa infection of the pubic symphysis occurred in intravenous abusers of pentazocine hydrochloride and pyribenzamine. Symptoms included suprapubic pain when walking, bilateral inguinal pain, and pain caused by hip flexion and rotation. Cultures of material taken by joint aspiration and open biopsy yielded P. aeruginosa in three patients and P. aeruginosa, P. maltophilia, and Corynebacterium in the fourth. All four responded to antibiotic treatment and open debridement but were lost to follow-up. Recent reports of P. aeruginosa arthritis in intravenous drug abusers are discussed. The concept of infective synchondritis as a distinct entity is suggested.
四例耻骨联合铜绿假单胞菌感染发生在静脉注射盐酸喷他佐辛和曲吡那敏的滥用者中。症状包括行走时耻骨上区疼痛、双侧腹股沟疼痛以及髋关节屈伸和旋转时引起的疼痛。通过关节穿刺和开放活检采集的样本培养，三名患者培养出铜绿假单胞菌，第四名患者培养出铜绿假单胞菌、嗜麦芽窄食单胞菌和棒状杆菌。所有四名患者对抗生素治疗和开放清创均有反应，但均失访。讨论了近期关于静脉注射药物滥用者铜绿假单胞菌关节炎的报道。提出了感染性软骨炎作为一种独特实体的概念。
