McGlone T P, Bernie W A, Elliott D W
Arch Surg. 1982 May;117(5):595-9. doi: 10.1001/archsurg.1982.01380290055010.
Of 460 cases of colon cancer treated between 1972 and 1976, 24 were unusual. These patients required en bloc resection of the colon with one or more adjacent organs for dense adhesions between the colon and these organs. In 66% of the cases these adhesions represented microscopic tumor invasion. Lymph nodes were positive for disease, stage C-3, in only four specimens. The pathologic features of the tumor were well differentiated in 87%. The operative mortality was 8% and two patients died of recurrent disease one and three years postoperatively. One man is alive seven years postoperatively with recurrent disease. Nineteen patients (79%) are alive five to nine years following surgery with no evidence of disease. A comparison with patients with similarly staged Dukes' B and C disease shows a substantially improved survival at five years when extended operation is performed.
在1972年至1976年期间接受治疗的460例结肠癌病例中，有24例情况特殊。这些患者因结肠与一个或多个相邻器官之间存在致密粘连，需要将结肠与这些器官整块切除。在66%的病例中，这些粘连代表显微镜下的肿瘤侵犯。仅4份标本的淋巴结有疾病阳性，分期为C-3期。肿瘤的病理特征87%为高分化。手术死亡率为8%，两名患者术后1年和3年死于复发性疾病。一名男性术后7年因复发性疾病存活。19名患者（79%）术后5至9年存活，无疾病证据。与分期相似的杜克B期和C期疾病患者相比，进行扩大手术时5年生存率有显著提高。
