Derizhanova I S, Ratner N I, Filatov V V
Arkh Patol. 1982;44(2):51-4.
A carcinoid tumor of the mediastinum in a man of 58, incidentally detected at a roentgenological examination is described. Its histological structure was identical with that of carcinoids of other localization. The tumor cells contained argyrophilic granules. The patient died 41/2 years after the operation in the presence of extensive lymphogenic and hematogenic metastases. The authors believe that signs such as cellular and nuclear polymorphism, outgrowth of the tumor cells into the capsule, lymph vessels detectable even in limited area should be considered as criteria of malignancy of the neoplasma and the basis for prescription of radiation and chemotherapy.
本文描述了一名58岁男性纵隔类癌肿瘤,该肿瘤在一次X线检查中偶然发现。其组织学结构与其他部位类癌相同。肿瘤细胞含有嗜银颗粒。患者术后4年半因广泛的淋巴源性和血行性转移而死亡。作者认为,细胞和核多形性、肿瘤细胞向包膜外生长、即使在有限区域也可检测到的淋巴管等征象应被视为肿瘤恶性的标准以及放疗和化疗处方的依据。