Litvinova L V, Solov'ev Iu N
Arkh Patol. 1982;44(2):9-16.
Ewing's tumor is a rare malignant neoplasm of the bone the histogenesis of which still remains obscure. The present study was aimed at the electron microscopic determination of the structural characteristics of the neoplasm' cell elements. Tumor tissue from 4 patients operated on elements. Tumor tissue from 4 patients operated on at the Cancer Research Centre of the USSR AMS was examined. The methodical approach was modified in this study: with due account to the zonal distribution of organelles in tumor cells of the bone, 100 preparations from one block were examined in the electron microscope. The tumor cell elements were shown to be predominantly forms of low differentiation. Detailed examinations revealed signs of structural-functional differentiation of the cells mostly indicative of the angiogenic nature of Ewing's tumor.
尤因肉瘤是一种罕见的骨恶性肿瘤，其组织发生仍不清楚。本研究旨在通过电子显微镜确定该肿瘤细胞成分的结构特征。对苏联医学科学院癌症研究中心4例接受手术的患者的肿瘤组织进行了检查。本研究对方法进行了改进：考虑到骨肿瘤细胞中细胞器的区域分布，在电子显微镜下检查了来自一个组织块的100份标本。结果显示肿瘤细胞成分主要为低分化形式。详细检查发现细胞存在结构-功能分化迹象，大多表明尤因肉瘤具有血管生成性质。
