Klawans H L, Stein R W, Tanner C M, Goetz C G
Arch Neurol. 1982 May;39(5):302-4. doi: 10.1001/archneur.1982.00510170044012.
A 50-year-old woman with carbon monoxide (CO)-induced parkinsonism was found to have bilateral lucencies of the globus pallidus on computed tomographic (CT) scan consistent with old necrotic lesions. She showed no clinical response to levodopa therapy, although she did improve with anticholinergic therapy. It is suggested that the parkinsonism in this patient is due to the pallidal lesions demonstrated on CT scan, and that such pallidal-related parkinsonism may not respond to dopaminergic therapy.
一名50岁患有一氧化碳(CO)诱发帕金森症的女性,在计算机断层扫描(CT)中发现双侧苍白球有透亮区,与陈旧性坏死性病变相符。她对左旋多巴治疗无临床反应,不过抗胆碱能治疗使其症状有所改善。提示该患者的帕金森症是由CT扫描显示的苍白球病变所致,且这种与苍白球相关的帕金森症可能对多巴胺能治疗无反应。