Leimert J T, Armitage J O, Dick F R
Am J Clin Pathol. 1978 Oct;70(4):706-8. doi: 10.1093/ajcp/70.4.706.
The case of a patient with myelofibrosis and painful osteolytic lesions is described. Biopsy of the involved bone demonstrated myeloid proliferation. Foci of myeloid metaplasia may occasionally result in clinical disability, with bone pain and rarefaction. Myeloid metaplasia should be considered when these symptoms and signs occur in the setting of myelofibrosis. The role of radiation therapy as a palliative maneuver remains uncertain.
本文描述了一名患有骨髓纤维化和疼痛性溶骨性病变的患者病例。受累骨骼的活检显示有髓系增殖。髓外造血灶偶尔可能导致临床残疾，出现骨痛和骨质稀疏。当骨髓纤维化患者出现这些症状和体征时，应考虑髓外造血。放射治疗作为一种姑息性手段的作用仍不确定。
